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What Can We Learn From Fitness Landscapes?

A combinatorially complete data set consists of studies of all possible combinations of a set of mutant sites in a gene or mutant alleles in a genome. Among the most robust conclusions from these studies is that epistasis between beneficial mutations often shows a pattern of diminishing returns, in...

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Vydáno v:Curr Opin Microbiol
Hlavní autor: Hartl, Daniel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254422/
https://ncbi.nlm.nih.gov/pubmed/25444121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2014.08.001
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