A Thorough QT Study to Evaluate the Effects of a Supratherapeutic Dose of Sertraline on Cardiac Repolarization in Healthy Subjects

The effect of steady‐state supratherapeutic sertraline (Zoloft) on QT interval was assessed in a single‐center, randomized, 3‐way crossover, double‐blind, placebo‐ and moxifloxacin‐controlled thorough QT study. Healthy adults received sertraline 400 mg/day, moxifloxacin 400 mg, and placebo, with a w...

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書目詳細資料
發表在:Clin Pharmacol Drug Dev
Main Authors: Abbas, Richat, Riley, Steve, LaBadie, Robert R., Bachinsky, Mary, Chappell, Phillip B., Crownover, Penelope H., Damle, Bharat
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7187253/
https://ncbi.nlm.nih.gov/pubmed/31777203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.749
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