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A Thorough QT Study To Evaluate the Effects of Therapeutic and Supratherapeutic Doses of Delafloxacin on Cardiac Repolarization

A randomized, double-blind, placebo-controlled, 4-period crossover study was conducted in 52 healthy adults to assess the effect of delafloxacin on the corrected QT (QTc) interval. The QT interval, corrected for heart rate using Fridericia's formula (QTcF), was determined predose and at 0.5, 1,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Litwin, Jeffrey S., Benedict, Michael S., Thorn, Michael D., Lawrence, Laura E., Cammarata, Sue K., Sun, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432193/
https://ncbi.nlm.nih.gov/pubmed/25845864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04813-14
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