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Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors

Immunotherapies are used as adjuvant therapies for cancers. However, knowledge of how traditional cancer treatments affect immunotherapies is limited. Using mouse models, we demonstrate that tumor-draining lymph nodes (TdLNs) are critical for tumor antigen-specific T cell response. However, removing...

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Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Zhao, Xianda, Kassaye, Beminet, Wangmo, Dechen, Lou, Emil, Subramanian, Subbaya
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186531/
https://ncbi.nlm.nih.gov/pubmed/32344378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101056
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