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Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors

Immunotherapies are used as adjuvant therapies for cancers. However, knowledge of how traditional cancer treatments affect immunotherapies is limited. Using mouse models, we demonstrate that tumor-draining lymph nodes (TdLNs) are critical for tumor antigen-specific T cell response. However, removing...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Zhao, Xianda, Kassaye, Beminet, Wangmo, Dechen, Lou, Emil, Subramanian, Subbaya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186531/
https://ncbi.nlm.nih.gov/pubmed/32344378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101056
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