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Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors

Immunotherapies are used as adjuvant therapies for cancers. However, knowledge of how traditional cancer treatments affect immunotherapies is limited. Using mouse models, we demonstrate that tumor-draining lymph nodes (TdLNs) are critical for tumor antigen-specific T cell response. However, removing...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Zhao, Xianda, Kassaye, Beminet, Wangmo, Dechen, Lou, Emil, Subramanian, Subbaya
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7186531/
https://ncbi.nlm.nih.gov/pubmed/32344378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101056
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