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Pharmacokinetics and pharmacodynamics of therapeutic antibodies in tumors and tumor-draining lymph nodes

The signaling axis from the primary tumor to the tumor-draining lymph node (TDLN) has emerged as a crucial mediator for the efficacy of immunotherapies in neoadjuvant settings, challenging the primary use of immunotherapy in adjuvant settings. TDLNs are regarded as highly opportunistic sites for can...

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Detalhes bibliográficos
Publicado no:Math Biosci Eng
Main Authors: Salgado, Eric, Cao, Yanguang
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935407/
https://ncbi.nlm.nih.gov/pubmed/33525083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/mbe.2021006
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