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Multivariate analysis reveals activation-primed fibroblast geometric states in engineered 3D tumor microenvironments

Fibroblasts are a heterogeneous group of cells comprising subpopulations that have been found to be activated in the stromal microenvironment that regulates tumor initiation and growth. The underlying mechanisms of such selective activation of fibroblasts are not understood. We propose that the intr...

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Dades bibliogràfiques
Publicat a:Mol Biol Cell
Autors principals: Venkatachalapathy, Saradha, Jokhun, Doorgesh Sharma, Shivashankar, G. V.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185960/
https://ncbi.nlm.nih.gov/pubmed/32023167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-08-0420
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