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Multivariate analysis reveals activation-primed fibroblast geometric states in engineered 3D tumor microenvironments

Fibroblasts are a heterogeneous group of cells comprising subpopulations that have been found to be activated in the stromal microenvironment that regulates tumor initiation and growth. The underlying mechanisms of such selective activation of fibroblasts are not understood. We propose that the intr...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Venkatachalapathy, Saradha, Jokhun, Doorgesh Sharma, Shivashankar, G. V.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185960/
https://ncbi.nlm.nih.gov/pubmed/32023167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-08-0420
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