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Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors
Cells in tissues undergo transdifferentiation programs when stimulated by specific mechanical and biochemical signals. While seminal studies have demonstrated that exogenous biochemical factors can reprogram somatic cells into pluripotent stem cells, the critical roles played by mechanical signals i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003522/ https://ncbi.nlm.nih.gov/pubmed/29735717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714770115 |
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