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Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors

Cells in tissues undergo transdifferentiation programs when stimulated by specific mechanical and biochemical signals. While seminal studies have demonstrated that exogenous biochemical factors can reprogram somatic cells into pluripotent stem cells, the critical roles played by mechanical signals i...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Roy, Bibhas, Venkatachalapathy, Saradha, Ratna, Prasuna, Wang, Yejun, Jokhun, Doorgesh Sharma, Nagarajan, Mallika, Shivashankar, G. V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003522/
https://ncbi.nlm.nih.gov/pubmed/29735717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714770115
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