Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors

Cells in tissues undergo transdifferentiation programs when stimulated by specific mechanical and biochemical signals. While seminal studies have demonstrated that exogenous biochemical factors can reprogram somatic cells into pluripotent stem cells, the critical roles played by mechanical signals i...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Roy, Bibhas, Venkatachalapathy, Saradha, Ratna, Prasuna, Wang, Yejun, Jokhun, Doorgesh Sharma, Nagarajan, Mallika, Shivashankar, G. V.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003522/
https://ncbi.nlm.nih.gov/pubmed/29735717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714770115
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