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Cell-state dynamics and therapeutic resistance in melanoma from the perspective of MITF and IFNγ pathways
Targeted therapy and immunotherapy have greatly improved the prognosis of patients with metastatic melanoma, but resistance to these therapeutic modalities limits the percentage of patients with long-lasting responses. Accumulating evidence indicates that a persisting subpopulation of melanoma cells...
Enregistré dans:
| Publié dans: | Nat Rev Clin Oncol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7185899/ https://ncbi.nlm.nih.gov/pubmed/30967646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0204-6 |
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