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Cell-state dynamics and therapeutic resistance in melanoma from the perspective of MITF and IFNγ pathways

Targeted therapy and immunotherapy have greatly improved the prognosis of patients with metastatic melanoma, but resistance to these therapeutic modalities limits the percentage of patients with long-lasting responses. Accumulating evidence indicates that a persisting subpopulation of melanoma cells...

詳細記述

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書誌詳細
出版年:Nat Rev Clin Oncol
主要な著者: Bai, Xue, Fisher, David E., Flaherty, Keith T.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185899/
https://ncbi.nlm.nih.gov/pubmed/30967646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0204-6
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