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Cell-state dynamics and therapeutic resistance in melanoma from the perspective of MITF and IFNγ pathways

Targeted therapy and immunotherapy have greatly improved the prognosis of patients with metastatic melanoma, but resistance to these therapeutic modalities limits the percentage of patients with long-lasting responses. Accumulating evidence indicates that a persisting subpopulation of melanoma cells...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Bai, Xue, Fisher, David E., Flaherty, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185899/
https://ncbi.nlm.nih.gov/pubmed/30967646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41571-019-0204-6
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