Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope

The heavy chain IGHV1-69 germline gene exhibits a high level of polymorphism and shows biased use in protective antibody (Ab) responses to infections and vaccines. It is also highly expressed in several B cell malignancies and autoimmune diseases. G6 is an anti-idiotypic monoclonal Ab that selective...

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Publicado no:Cell Rep
Main Authors: Avnir, Yuval, Prachanronarong, Kristina L., Zhang, Zhen, Hou, Shurong, Peterson, Eric C., Sui, Jianhua, Zayed, Hatem, Kurella, Vinodh B., McGuire, Andrew T., Stamatatos, Leonidas, Hilbert, Brendan J., Bohn, Markus-Frederik, Kowalik, Timothy F., Jensen, Jeffrey D., Finberg, Robert W., Wang, Jennifer P., Goodall, Margaret, Jefferis, Roy, Zhu, Quan, Kurt Yilmaz, Nese, Schiffer, Celia A., Marasco, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185437/
https://ncbi.nlm.nih.gov/pubmed/29241550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.11.056
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