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Rational Design of a Humanized Antibody Inhibitor of Cathepsin B

Cathepsin B (CTSB) is an abundant cysteine protease that functions in both endolysosomal compartments and extracellular regions. A considerable number of preclinical and clinical studies indicate that CTSB is implicated in many human diseases. Expression levels and activity of CTSB significantly cor...

詳細記述

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書誌詳細
出版年:Biochemistry
主要な著者: Dai, Zhefu, Cheng, Qinqin, Zhang, Yong
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184884/
https://ncbi.nlm.nih.gov/pubmed/32212642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00046
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