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Rational Design of a Humanized Antibody Inhibitor of Cathepsin B
Cathepsin B (CTSB) is an abundant cysteine protease that functions in both endolysosomal compartments and extracellular regions. A considerable number of preclinical and clinical studies indicate that CTSB is implicated in many human diseases. Expression levels and activity of CTSB significantly cor...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7184884/ https://ncbi.nlm.nih.gov/pubmed/32212642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00046 |
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