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Rho-kinase ROCK inhibitors reduce oligomeric tau protein
Neurofibrillary tangles, one of the pathological hallmarks of Alzheimer’s disease, consist of highly phosphorylated tau proteins. Tau protein binds to microtubules and is best known for its role in regulating microtubule dynamics. However, if tau protein is phosphorylated by activated major tau kina...
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| Publicat a: | Neurobiol Aging |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183001/ https://ncbi.nlm.nih.gov/pubmed/31982202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.12.009 |
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