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Autophagy and Tau Protein

Neurofibrillary tangles, which consist of highly phosphorylated tau protein, and senile plaques (SPs) are pathological hallmarks of Alzheimer’s disease (AD). In swollen axons, many autophagic vacuoles are observed around SP in the AD brain. This suggests that autophagy function is disturbed in AD. W...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hamano, Tadanori, Enomoto, Soichi, Shirafuji, Norimichi, Ikawa, Masamichi, Yamamura, Osamu, Yen, Shu-Hui, Nakamoto, Yasunari
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8303176/
https://ncbi.nlm.nih.gov/pubmed/34299093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22147475
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