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Rho-kinase ROCK inhibitors reduce oligomeric tau protein
Neurofibrillary tangles, one of the pathological hallmarks of Alzheimer’s disease, consist of highly phosphorylated tau proteins. Tau protein binds to microtubules and is best known for its role in regulating microtubule dynamics. However, if tau protein is phosphorylated by activated major tau kina...
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| Pubblicato in: | Neurobiol Aging |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183001/ https://ncbi.nlm.nih.gov/pubmed/31982202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.12.009 |
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