SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans

Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian cells, the metabolic switch from mitochondrial respiration to aerobic glycolysis provides flexibility to sustain cellular energy in pathophys...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Krabbendam, Inge E., Honrath, Birgit, Dilberger, Benjamin, Iannetti, Eligio F., Branicky, Robyn S., Meyer, Tammo, Evers, Bernard, Dekker, Frank J., Koopman, Werner J. H., Beyrath, Julien, Bano, Daniele, Schmidt, Martina, Bakker, Barbara M., Hekimi, Siegfried, Culmsee, Carsten, Eckert, Gunter P., Dolga, Amalia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181639/
https://ncbi.nlm.nih.gov/pubmed/32327637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2458-4
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