Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression

Inflammasomes can prevent systemic dissemination of enteropathogenic bacteria. As adapted pathogens including Salmonella Typhimurium (S. Tm) have evolved evasion strategies, it has remained unclear when and where inflammasomes restrict their dissemination. Bacterial population dynamics establish tha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mucosal Immunol
Prif Awduron: Hausmann, Annika, Böck, Desirée, Geiser, Petra, Berthold, Dorothée L., Fattinger, Stefan A., Furter, Markus, Bouman, Judith A., Barthel-Scherrer, Manja, Lang, Crispin M., Bakkeren, Erik, Kolinko, Isabel, Diard, Médéric, Bumann, Dirk, Slack, Emma, Regoes, Roland R., Pilhofer, Martin, Sellin, Mikael E., Hardt, Wolf-Dietrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group US 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181392/
https://ncbi.nlm.nih.gov/pubmed/31953493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0247-0
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