Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression

Inflammasomes can prevent systemic dissemination of enteropathogenic bacteria. As adapted pathogens including Salmonella Typhimurium (S. Tm) have evolved evasion strategies, it has remained unclear when and where inflammasomes restrict their dissemination. Bacterial population dynamics establish tha...

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Udgivet i:Mucosal Immunol
Main Authors: Hausmann, Annika, Böck, Desirée, Geiser, Petra, Berthold, Dorothée L., Fattinger, Stefan A., Furter, Markus, Bouman, Judith A., Barthel-Scherrer, Manja, Lang, Crispin M., Bakkeren, Erik, Kolinko, Isabel, Diard, Médéric, Bumann, Dirk, Slack, Emma, Regoes, Roland R., Pilhofer, Martin, Sellin, Mikael E., Hardt, Wolf-Dietrich
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181392/
https://ncbi.nlm.nih.gov/pubmed/31953493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0247-0
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