Bacterial detection by NAIP/NLRC4 elicits prompt contractions of intestinal epithelial cell layers

The gut epithelium serves to maximize the surface for nutrient and fluid uptake, but at the same time must provide a tight barrier to pathogens and remove damaged intestinal epithelial cells (IECs) without jeopardizing barrier integrity. How the epithelium coordinates these tasks remains a question...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Samperio Ventayol, Pilar, Geiser, Petra, Di Martino, Maria Letizia, Florbrant, Alexandra, Fattinger, Stefan A., Walder, Naemi, Sima, Eduardo, Shao, Feng, Gekara, Nelson O., Sundbom, Magnus, Hardt, Wolf-Dietrich, Webb, Dominic-Luc, Hellström, Per M., Eriksson, Jens, Sellin, Mikael E.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072224/
https://ncbi.nlm.nih.gov/pubmed/33846244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013963118
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