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Live-Cell Imaging and Quantification of PolyQ Aggregates by Stimulated Raman Scattering of Selective Deuterium Labeling

[Image: see text] Polyglutamine (polyQ) diseases are a group of neurodegenerative disorders, involving the deposition of aggregation-prone proteins with long polyQ expansions. However, the cytotoxic roles of these aggregates remain highly controversial, largely due to a lack of proper tools for quan...

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Bibliografiske detaljer
Udgivet i:ACS Cent Sci
Main Authors: Miao, Kun, Wei, Lu
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2020
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181319/
https://ncbi.nlm.nih.gov/pubmed/32341997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b01196
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