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Thiol-Reactive PODS-Bearing Bifunctional Chelators for the Development of EGFR-Targeting [(18)F]AlF-Affibody Conjugates
Site-selective bioconjugation of cysteine-containing peptides and proteins is currently achieved via a maleimide–thiol reaction (Michael addition). When maleimide-functionalized chelators are used and the resulting bioconjugates are subsequently radiolabeled, instability has been observed both durin...
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| Gepubliceerd in: | Molecules |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
MDPI
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7180749/ https://ncbi.nlm.nih.gov/pubmed/32235296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071562 |
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