Synthesis and Evaluation of Artificial Nucleic Acid Bearing an Oxanorbornane Scaffold

Natural oligonucleotides have many rotatable single bonds, and thus their structures are inherently flexible. Structural flexibility leads to an entropic loss when unwound oligonucleotides form a duplex with single-stranded DNA or RNA. An effective approach to reduce such entropic loss in the duplex...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Komine, Hibiki, Mori, Shohei, Morihiro, Kunihiko, Ishida, Kenta, Okuda, Takumi, Kasahara, Yuuya, Aoyama, Hiroshi, Yamaguchi, Takao, Obika, Satoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180610/
https://ncbi.nlm.nih.gov/pubmed/32283778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071732
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