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An Excimer Clamp for Measuring Damaged Base Excision by the DNA Repair Enzyme NTH1

Direct measurement of DNA repair enzyme activities is important both for basic study of cellular repair pathways as well as for potential new translational applications in their associated diseases. NTH1, a major glycosylase targeting oxidized pyrimidines, prevents mutations arising from this damage...

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Jun, Yong Woong, Wilson, David L., Kietrys, Anna M., Lotsof, Elizabeth R., Conlon, Savannah G., David, Sheila S., Kool, Eric T.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180134/
https://ncbi.nlm.nih.gov/pubmed/32109332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202001516
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