Induction of base excision repair enzymes NTH1 and APE1 in rat spleen following aniline exposure

Mechanisms by which aniline exposure elicits splenotoxicity, especially a tumorigenic response, are not well-understood. Earlier, we have shown that aniline exposure leads to oxidative DNA damage and up-regulation of OGG1 and NEIL1/2 DNA glycosylases in rat spleen. However, the contribution of endon...

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Bibliografiske detaljer
Main Authors: Ma, Huaxian, Wang, Jianling, Abdel-Rahman, Sherif Z., Boor, Paul J., Khan, M. Firoze
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725747/
https://ncbi.nlm.nih.gov/pubmed/23352893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.01.005
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