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Oxidative DNA damage and its repair in rat spleen following subchronic exposure to aniline
The mechanisms by which aniline exposure elicits splenotoxic response, especially the tumorigenic response, are not well-understood. Splenotoxicity of aniline is associated with iron overload and generation of reactive oxygen species (ROS) which can cause oxidative damage to DNA, proteins and lipids...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614128/ https://ncbi.nlm.nih.gov/pubmed/18793663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.08.010 |
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