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Myristoylation of LMCD1 leads to its species-specific derepression of E2F1 and NFATc1 in the modulation of CDC6 and IL-33 expression during development of vascular lesions

OBJECTIVE: In view of our previous observations on differential expression of LIM and cysteine-rich domains 1 (LMCD1) in human versus rodents, we asked the question whether LMCD1 plays a species-specific role in the development of vascular lesions. APPROACH AND REULTS: A combination of genetic, mole...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Govatati, Suresh, Pichavaram, Prahalathan, Janjanam, Jagadeesh, Guo, Liang, Virmani, Renu, Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180120/
https://ncbi.nlm.nih.gov/pubmed/32160773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314147
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