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Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib

Tyrosine kinase inhibitors revolutionized cancer therapy but still evoke strong adverse effects that can dramatically reduce patients’ quality of life. One possibility to enhance drug safety is the exploitation of prodrug strategies to selectively activate a drug inside the tumor tissue. In this stu...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Bielec, Bjoern, Poetsch, Isabella, Ahmed, Esra, Heffeter, Petra, Keppler, Bernhard K., Kowol, Christian R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179202/
https://ncbi.nlm.nih.gov/pubmed/32143435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051149
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