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Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias

Ryanodine receptor 2 (RyR2) and SERCA2a are two major players in myocyte calcium (Ca) cycling that are modulated physiologically, affected by disease and thus considered to be potential targets for cardiac disease therapy. However, how RyR2 and SERCA2a influence each others’ activities, as well as t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Liu, Bin, Lou, Qing, Smith, Heather, Velez-Cortes, Florencia, Dillmann, Wolfgang H., Knollmann, Björn C., Armoundas, Antonis A., Györke, Sándor
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178036/
https://ncbi.nlm.nih.gov/pubmed/32260593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072535
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