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Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias

Ryanodine receptor 2 (RyR2) and SERCA2a are two major players in myocyte calcium (Ca) cycling that are modulated physiologically, affected by disease and thus considered to be potential targets for cardiac disease therapy. However, how RyR2 and SERCA2a influence each others’ activities, as well as t...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Liu, Bin, Lou, Qing, Smith, Heather, Velez-Cortes, Florencia, Dillmann, Wolfgang H., Knollmann, Björn C., Armoundas, Antonis A., Györke, Sándor
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178036/
https://ncbi.nlm.nih.gov/pubmed/32260593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072535
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