Platelet Activation in Heparin-Induced Thrombocytopenia is Followed by Platelet Death via Complex Apoptotic and Non-Apoptotic Pathways

Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction characterized by thrombocytopenia and a high risk for venous or arterial thrombosis. HIT is caused by antibodies that recognize complexes of platelet factor 4 and heparin. The pathogenic mechanisms of this condition are not fully und...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mordakhanova, Elmira R., Nevzorova, Tatiana A., Synbulatova, Gulnaz E., Rauova, Lubica, Weisel, John W., Litvinov, Rustem I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177543/
https://ncbi.nlm.nih.gov/pubmed/32272655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072556
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