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Tumor Milieu Controlled by RB Tumor Suppressor

The RB gene is one of the most frequently mutated genes in human cancers. Canonically, RB exerts its tumor suppressive activity through the regulation of the G1/S transition during cell cycle progression by modulating the activity of E2F transcription factors. However, aberration of the RB gene is m...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kitajima, Shunsuke, Li, Fengkai, Takahashi, Chiaki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177274/
https://ncbi.nlm.nih.gov/pubmed/32244804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072450
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