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Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation

The Retinoblastoma (RB) tumor suppressor regulates G(1)/S transition during cell cycle progression by modulating the activity of E2F transcription factors. The RB pathway plays a central role in the suppression of most cancers, and RB mutation was initially discovered by virtue of its role in tumor...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Kitajima, Shunsuke, Takahashi, Chiaki
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581511/
https://ncbi.nlm.nih.gov/pubmed/28865172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13312
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