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Twists in views on RB functions in cellular signaling, metabolism and stem cells
One‐quarter of a century ago, identification of the human retinoblastoma gene (RB) loci proved Knudson's ‘two‐hit theory’ that tumor suppressor genes exist. Since then, numerous works delineated crucial roles for the RB protein (pRB)‐E2F transcription factor complex in G1‐S phase transition. In...
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| Publicado no: | Cancer Sci |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659297/ https://ncbi.nlm.nih.gov/pubmed/22448711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02284.x |
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