ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation

The retinoblastoma tumor suppressor gene (RB) product has been implicated in epigenetic control of gene expression owing to its ability to physically bind to many chromatin modifiers. However, the biological and clinical significance of this activity was not well elucidated. To address this, we perf...

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Detalhes bibliográficos
Main Authors: Shamma, Awad, Suzuki, Misa, Hayashi, Naoyuki, Kobayashi, Masahiko, Sasaki, Nobunari, Nishiuchi, Takumi, Doki, Yuichiro, Okamoto, Takahiro, Kohno, Susumu, Muranaka, Hayato, Kitajima, Shunsuke, Yamamoto, Ken-ichi, Takahashi, Chiaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753918/
https://ncbi.nlm.nih.gov/pubmed/23754744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01597-12
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