ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation

The retinoblastoma tumor suppressor gene (RB) product has been implicated in epigenetic control of gene expression owing to its ability to physically bind to many chromatin modifiers. However, the biological and clinical significance of this activity was not well elucidated. To address this, we perf...

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Autores principales: Shamma, Awad, Suzuki, Misa, Hayashi, Naoyuki, Kobayashi, Masahiko, Sasaki, Nobunari, Nishiuchi, Takumi, Doki, Yuichiro, Okamoto, Takahiro, Kohno, Susumu, Muranaka, Hayato, Kitajima, Shunsuke, Yamamoto, Ken-ichi, Takahashi, Chiaki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753918/
https://ncbi.nlm.nih.gov/pubmed/23754744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01597-12
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