A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires

Natively paired sequencing (NPS) of B cell receptors [variable heavy (VH) and light (VL)] and T cell receptors (TCRb and TCRa) is essential for the understanding of adaptive immunity in health and disease. Despite many recent technical advances, determining the VH:VL or TCRb:a repertoire with high a...

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Publicat a:Sci Adv
Autors principals: Tanno, Hidetaka, McDaniel, Jonathan R., Stevens, Christopher A., Voss, William N., Li, Jie, Durrett, Russell, Lee, Jiwon, Gollihar, Jimmy, Tanno, Yuri, Delidakis, George, Pothukuchy, Arti, Ellefson, Jared W., Goronzy, Jörg J., Maynard, Jennifer A., Ellington, Andrew D., Ippolito, Gregory C., Georgiou, George
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176429/
https://ncbi.nlm.nih.gov/pubmed/32426460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9093
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