A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires

Natively paired sequencing (NPS) of B cell receptors [variable heavy (VH) and light (VL)] and T cell receptors (TCRb and TCRa) is essential for the understanding of adaptive immunity in health and disease. Despite many recent technical advances, determining the VH:VL or TCRb:a repertoire with high a...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Tanno, Hidetaka, McDaniel, Jonathan R., Stevens, Christopher A., Voss, William N., Li, Jie, Durrett, Russell, Lee, Jiwon, Gollihar, Jimmy, Tanno, Yuri, Delidakis, George, Pothukuchy, Arti, Ellefson, Jared W., Goronzy, Jörg J., Maynard, Jennifer A., Ellington, Andrew D., Ippolito, Gregory C., Georgiou, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176429/
https://ncbi.nlm.nih.gov/pubmed/32426460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9093
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