A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires

Natively paired sequencing (NPS) of B cell receptors [variable heavy (VH) and light (VL)] and T cell receptors (TCRb and TCRa) is essential for the understanding of adaptive immunity in health and disease. Despite many recent technical advances, determining the VH:VL or TCRb:a repertoire with high a...

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Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Tanno, Hidetaka, McDaniel, Jonathan R., Stevens, Christopher A., Voss, William N., Li, Jie, Durrett, Russell, Lee, Jiwon, Gollihar, Jimmy, Tanno, Yuri, Delidakis, George, Pothukuchy, Arti, Ellefson, Jared W., Goronzy, Jörg J., Maynard, Jennifer A., Ellington, Andrew D., Ippolito, Gregory C., Georgiou, George
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176429/
https://ncbi.nlm.nih.gov/pubmed/32426460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9093
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