A facile technology for the high-throughput sequencing of the paired VH:VL and TCRβ:TCRα repertoires

Natively paired sequencing (NPS) of B cell receptors [variable heavy (VH) and light (VL)] and T cell receptors (TCRb and TCRa) is essential for the understanding of adaptive immunity in health and disease. Despite many recent technical advances, determining the VH:VL or TCRb:a repertoire with high a...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Tanno, Hidetaka, McDaniel, Jonathan R., Stevens, Christopher A., Voss, William N., Li, Jie, Durrett, Russell, Lee, Jiwon, Gollihar, Jimmy, Tanno, Yuri, Delidakis, George, Pothukuchy, Arti, Ellefson, Jared W., Goronzy, Jörg J., Maynard, Jennifer A., Ellington, Andrew D., Ippolito, Gregory C., Georgiou, George
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176429/
https://ncbi.nlm.nih.gov/pubmed/32426460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay9093
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