STING couples with PI3K to regulate actin reorganization during BCR activation

The adaptor protein, STING (stimulator of interferon genes), has been rarely studied in adaptive immunity. We used Sting KO mice and a patient’s mutated STING cells to study the effect of STING deficiency on B cell development, differentiation, and BCR signaling. We found that STING deficiency promo...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Jing, Yukai, Dai, Xin, Yang, Lu, Kang, Danqing, Jiang, Panpan, Li, Na, Cheng, Jiali, Li, Jingwen, Miller, Heather, Ren, Boxu, Gong, Quan, Yin, Wei, Liu, Zheng, Mattila, Pieta K., Ning, Qin, Sun, Jinqiao, Yu, Bing, Liu, Chaohong
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176427/
https://ncbi.nlm.nih.gov/pubmed/32494627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax9455
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