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Association of PI-3 Kinase with PAK1 Leads to Actin Phosphorylation and Cytoskeletal Reorganization

The family of p21-activated kinases (PAKs) have been implicated in the rearrangement of actin cytoskeleton by acting downstream of the small GTPases Rac and Cdc42. Here we report that even though Cdc42/Rac1 or Akt are not activated, phosphatidylinositol-3 (PI-3) kinase activation induces PAK1 kinase...

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Detalhes bibliográficos
Main Authors: Papakonstanti, Evangelia A., Stournaras, Christos
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC117954/
https://ncbi.nlm.nih.gov/pubmed/12181358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.02-01-0599
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