TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase.

Glomerular permeability for macromolecules depends partially on proper attachment of the glomerular epithelial cells (GEC) to the glomerular basement membrane (GBM). The latter requires integrity of the actin cytoskeleton, which in turn is regulated by specific actin-associated proteins. Since sever...

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Hauptverfasser: Koukouritaki, S. B., Vardaki, E. A., Papakonstanti, E. A., Lianos, E., Stournaras, C., Emmanouel, D. S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Feinstein Institute for Medical Research 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230436/
https://ncbi.nlm.nih.gov/pubmed/10415163
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