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Actin reorganization is required for the formation of polarized BCR signalosomes in response to both soluble and membrane-associated antigens()

B-cells encounter both soluble (sAg) and membrane-associated antigens (mAg) in the secondary lymphoid tissue, yet how the physical form of Ag modulates B-cell activation remains unclear. This study compares actin reorganization and its role in BCR signalosome formation in mAg- and sAg-stimulated B-c...

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Detalhes bibliográficos
Main Authors: Liu, Chaohong, Miller, Heather, Orlowski, Gregory, Hang, Haiyin, Upadhyaya, Arpita, Song, Wenxia
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312033/
https://ncbi.nlm.nih.gov/pubmed/22387556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103065
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