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Intellectual disability-associated SMARCB1 mutations reveal a nucleosome acidic patch interaction site that potentiates mSWI/SNF chromatin remodeling
Mammalian SWI/SNF (BAF) complexes are multi-component machines that remodel chromatin architecture. Dissection of the subunit- and domain- specific contributions to complex activities is required to advance mechanistic understanding. Here we examine the molecular, structural, and genome-wide regulat...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7175411/ https://ncbi.nlm.nih.gov/pubmed/31759698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.10.044 |
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