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A dorsal-ventral gradient of Wnt3a/β-catenin signals controls mouse hindgut extension and colon formation

Despite the importance of Wnt signaling for adult intestinal stem cell homeostasis and colorectal cancer, relatively little is known about its role in colon formation during embryogenesis. The development of the colon starts with the formation and extension of the hindgut. We show that Wnt3a is expr...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Garriock, Robert J., Chalamalasetty, Ravindra B., Zhu, JianJian, Kennedy, Mark W., Kumar, Amit, Mackem, Susan, Yamaguchi, Terry P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174843/
https://ncbi.nlm.nih.gov/pubmed/32156757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.185108
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