Transcriptional Profiling of Wnt3a Mutants Identifies Sp Transcription Factors as Essential Effectors of the Wnt/β-catenin Pathway in Neuromesodermal Stem Cells

Neuromesodermal (NM) stem cells reside in the primitive streak (PS) of gastrulating vertebrate embryos and generate precursors of the spinal cord and musculoskeletal system. Although Wnt3a/β-catenin signaling is crucial for NM stem cell maintenance and differentiation, few key transcriptional effect...

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Detalhes bibliográficos
Main Authors: Dunty, William C., Kennedy, Mark W. L., Chalamalasetty, Ravindra B., Campbell, Kenneth, Yamaguchi, Terry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901714/
https://ncbi.nlm.nih.gov/pubmed/24475213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087018
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