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A new gain-of-function mouse line to study the role of Wnt3a in development and disease
Wnt/β-catenin signals are important regulators of embryonic and adult stem cell self-renewal and differentiation and play causative roles in tumorigenesis. Purified recombinant Wnt3a protein, or Wnt3a-conditioned culture medium, has been widely used to study canonical Wnt signaling in vitro or ex vi...
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| Vydáno v: | Genesis |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6667172/ https://ncbi.nlm.nih.gov/pubmed/27411055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22959 |
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