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The Possible Role of Anti-Neu5Gc as an Obstacle in Xenotransplantation
Seventy to ninety percentage of preformed xenoreactive antibodies in human serum bind to the galactose-α(1,3)-galactose Gal epitope, and the creation of Gal knockout (KO) pigs has eliminated hyperacute rejection as a barrier to xenotransplantation. Now other glycan antigens are barriers to move ahea...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7174778/ https://ncbi.nlm.nih.gov/pubmed/32351506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00622 |
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