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Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans—An Evolutionary Perspective

The glycocalyx of human cells differs from that of many other mammals by the lack of the sialic acid N-glycolylneuraminic acid (Neu5Gc) and increased abundance of its precursor N-acetylneuraminic acid (Neu5Ac). Most humans also have circulating antibodies specifically targeting the non-human sialic...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Altman, Meghan O., Gagneux, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524697/
https://ncbi.nlm.nih.gov/pubmed/31134048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00789
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