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Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

MicroRNAs (miRNAs) are small RNAs that regulate gene expression. miRNAs are produced from primary miRNAs (pri-miRNAs), which are cleaved by Microprocessor. Microprocessor, therefore, plays a crucial role in determining the efficiency and precision of miRNA production, and thus the function of the fi...

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Publicado en:Nat Commun
Autores principales: Li, Shaohua, Nguyen, Trung Duc, Nguyen, Thuy Linh, Nguyen, Tuan Anh
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174388/
https://ncbi.nlm.nih.gov/pubmed/32317642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15674-2
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